Research use only. Read more

Anti-inflammatory

Thymosin Alpha-1

A 28-amino-acid peptide originally isolated from the thymus that modulates T-cell maturation and innate immune signalling; investigated as an immune-modulating adjunct.

Also known as: TA-1, Tα1, Zadaxin

Quick facts

Molecular weight

3,108 Da

Half-life

2 h

Frequency

twice weekly

Admins / wk

2

Routes

SubQ

Typical dose

1.60 mg–1.60 mg

Mechanism & positioning

A 28-amino-acid peptide originally isolated from the thymus that modulates T-cell maturation and innate immune signalling; investigated as an immune-modulating adjunct.

Researched for: T-cell maturation, innate immune modulation, antiviral adjunct research.

Reconstitution defaults

Default vial

5 mg

BAC water

2 mL

Concentration

2500 mcg/mL

Doses per vial

~3

Other stocked vial sizes: 10 mg.

Calculate with this peptide

References

  • Goldstein AL, Badamchian M, Expert Opin Biol Ther, 2004.

Related peptides in the Anti-inflammatory class

Frequently asked questions about Thymosin Alpha-1

What is the typical research dose range for Thymosin Alpha-1?
Thymosin Alpha-1 is most commonly investigated at 1.60 mg–1.60 mg per administration, twice weekly. Note: twice-weekly fixed dose. These values reflect documented research-stage protocols and are not medical recommendations.
What is the half-life of Thymosin Alpha-1?
Thymosin Alpha-1 has an approximate plasma half-life of 2 hours. Practical steady state is reached after roughly five half-lives — about 0 days under continuous administration.
How is Thymosin Alpha-1 administered in research protocols?
Published research uses subq administration. Typical reconstitution is 5 mg vial in 2 mL of bacteriostatic water, producing a concentration of 2500 mcg/mL.
What vial sizes are commonly available for Thymosin Alpha-1?
Common stocked vial sizes are 5 mg, 10 mg. The 5 mg vial is the most-used default in published protocols.