Cognitive

Semax

A heptapeptide analog of ACTH fragment 4-10 researched in Russian clinical literature for cognitive and neuroprotective effects.

Quick facts

Molecular weight

813 Da

Half-life

0.5 h

Frequency

daily

Admins / wk

Routes

Intranasal / SubQ

Typical dose

300 mcg–1.00 mg

Mechanism & positioning

A heptapeptide analog of ACTH fragment 4-10 researched in Russian clinical literature for cognitive and neuroprotective effects.

Researched for: BDNF expression, attention/memory modulation, neuroprotection.

Reconstitution defaults

Default vial

10 mg

BAC water

2 mL

Concentration

5000 mcg/mL

Doses per vial

~33

Other stocked vial sizes: 30 mg.

Calculate with this peptide

Documented pairwise interactions

caution
Semax + Selank
Often investigated together; consider stagger to attribute observed effects.

References

Kaplan AY et al., Neurosci Behav Physiol, 1996.

Related peptides in the Cognitive class

Frequently asked questions about Semax

What is the typical research dose range for Semax?

Semax is most commonly investigated at 300 mcg–1.00 mg per administration, daily. These values reflect documented research-stage protocols and are not medical recommendations.

What is the half-life of Semax?

Semax has an approximate plasma half-life of 0.5 hours. Practical steady state is reached after roughly five half-lives — about 0 days under continuous administration.

How is Semax administered in research protocols?

Published research uses intranasal or subq administration. Typical reconstitution is 10 mg vial in 2 mL of bacteriostatic water, producing a concentration of 5000 mcg/mL.

What vial sizes are commonly available for Semax?

Common stocked vial sizes are 10 mg, 30 mg. The 10 mg vial is the most-used default in published protocols.