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Oxytocin

A nonapeptide originally isolated from neurohypophyseal extracts; investigated for oxytocin-receptor agonism in affiliative-behaviour and stress-response research.

Research consideration: Dose stored in mcg; clinical literature typically uses IU. 1 IU ≈ 1.67 mcg.

Quick facts

Molecular weight

1,007 Da

Half-life

2 h

Frequency

daily

Admins / wk

7

Routes

SubQ / Intranasal

Typical dose

33 mcg–67 mcg

Mechanism & positioning

A nonapeptide originally isolated from neurohypophyseal extracts; investigated for oxytocin-receptor agonism in affiliative-behaviour and stress-response research.

Researched for: oxytocin receptor agonism, social/affiliative research models.

Reconstitution defaults

Default vial

5 mg

BAC water

2 mL

Concentration

2500 mcg/mL

Doses per vial

~151

Calculate with this peptide

References

  • Gimpl G, Fahrenholz F, Physiol Rev, 2001.

Related peptides in the Other class

Frequently asked questions about Oxytocin

What is the typical research dose range for Oxytocin?
Oxytocin is most commonly investigated at 33 mcg–67 mcg per administration, daily. Note: ~20–40 IU; 1 IU ≈ 1.67 mcg. These values reflect documented research-stage protocols and are not medical recommendations.
What is the half-life of Oxytocin?
Oxytocin has an approximate plasma half-life of 2 hours. Practical steady state is reached after roughly five half-lives — about 0 days under continuous administration.
How is Oxytocin administered in research protocols?
Published research uses subq or intranasal administration. Typical reconstitution is 5 mg vial in 2 mL of bacteriostatic water, producing a concentration of 2500 mcg/mL.
What vial sizes are commonly available for Oxytocin?
Common stocked vial sizes are 5 mg. The 5 mg vial is the most-used default in published protocols.
Anything important to know about Oxytocin before designing a protocol?
Dose stored in mcg; clinical literature typically uses IU. 1 IU ≈ 1.67 mcg.