Pigmentation
Melanotan II
A cyclic synthetic analog of α-melanocyte-stimulating hormone researched in pigmentation and appetite-suppression models.
Quick facts
Molecular weight
1,024 Da
Half-life
33 h
Frequency
daily
Admins / wk
7
Routes
SubQ
Typical dose
250 mcg–1.00 mg
Mechanism & positioning
A cyclic synthetic analog of α-melanocyte-stimulating hormone researched in pigmentation and appetite-suppression models.
Researched for: melanocortin receptor agonism, pigmentation models.
Reconstitution defaults
Default vial
10 mg
BAC water
2 mL
Concentration
5000 mcg/mL
Doses per vial
~40
Calculate with this peptide
Documented pairwise interactions
- warning
Melanotan II + PT-141
Both act on melanocortin receptors; overlapping mechanism increases probability of nausea and pressor effects.
References
- Dorr RT et al., Life Sci, 1996.
Frequently asked questions about Melanotan II
What is the typical research dose range for Melanotan II?
Melanotan II is most commonly investigated at 250 mcg–1.00 mg per administration, daily. These values reflect documented research-stage protocols and are not medical recommendations.
What is the half-life of Melanotan II?
Melanotan II has an approximate plasma half-life of 33 hours. Practical steady state is reached after roughly five half-lives — about 7 days under continuous administration.
How is Melanotan II administered in research protocols?
Published research uses subq administration. Typical reconstitution is 10 mg vial in 2 mL of bacteriostatic water, producing a concentration of 5000 mcg/mL.
What vial sizes are commonly available for Melanotan II?
Common stocked vial sizes are 10 mg. The 10 mg vial is the most-used default in published protocols.